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Razi (on whose commentary the above interpolation is based), regards this as a reference to the Prophet Muhammad. It seems, however, that the meaning is wider, embracing every believer, of whatever denomination, who is distressed at the blindness of people who attribute divinity or divine qualities to any being other than God Himself.
Commentators are divided in opinion as to the construction. The best opinion is that which I have adopted, referring back qilihi as a genitive governed by 'ilm in verse 85.
The Prophet was much troubled in mind by the Unfaith of the Quraish: xviii. 6. He is here told to leave them alone for a time, for the Truth must soon prevail.