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Lit., "towards it". Almost all of the classical commentators assume that this refers specifically, to the contempt with which the pagan Quraysh looked down upon the early followers of Muhammad, most of whom came from the poorest, lowliest strata of Meccan society. However, the abouve "saying" has undoubtedly a timeless import inasmuch as the poor and lowly have always been among the first to follow a prophet. Moreover, it may also have a bearing on our times as well, inasmuch as the materially powerful nations, whom their technological progress has blinded to many spiritual verities, are increasingly contemptuous of the weakness of those civilizations in which religion still plays an important, albeit largely formalistic, role; and so, not realizing that this very formalism and the ensuing cultural sterility, and not religious faith as such, is the innermost cause of that weakness, they attribute it to the influence of religion per se, saying as it were, "If religion were any good, we would have been the first in holding on to it" - thus "justifying" their own materialistic attitude and their refusal to be guided by spiritual considerations.
I.e., the concept of divine revelation as such, as is evident from the subsequent reference to the revelation of Moses.
Poor and powerless Muslims.
A great many of the early Muslims were in humble positions, and were despised by the Quraish leaders. 'If such men could see any good in Islam,' they said, 'there could be no good in it: if there had been any good in it, we should have been the first to see it!' The spiritually blind have such a good conceit of themselves! As they reject it, and as the Revelation is proved to have historic foundations, they can only call it "an old, old falsehood"!