أَمْ تَحْسَبُ أَنَّ أَكْثَرَهُمْ يَسْمَعُونَ أَوْ يَعْقِلُونَ ۚ إِنْ هُمْ إِلَّا كَٱلْأَنْعَـٰمِ ۖ بَلْ هُمْ أَضَلُّ سَبِيلًا Qur’an Al-Furqan (25:44)Am tahsabu anna aktharahum yasmaAAoona aw yaAAqiloona in hum illa kaalanAAami bal hum adallu sabeelan
Lit., "they are farther astray from the path [of truth]": see note [144] on 7:179 .
They neither pay attention, nor think for themselves. They only follow others blindly.
Generally, animals are obedient and loyal to their masters who care for them and they seem to know their way, whereas Meccan pagans are disobedient and ungrateful to their Lord and Sustainer, choosing to stray from the right path.